First Author | Su Y | Year | 2010 |
Journal | Biochem Biophys Res Commun | Volume | 391 |
Issue | 1 | Pages | 1039-42 |
PubMed ID | 19995555 | Mgi Jnum | J:156770 |
Mgi Id | MGI:4421346 | Doi | 10.1016/j.bbrc.2009.12.014 |
Citation | Su Y, et al. (2010) The novel function of nesfatin-1: anti-hyperglycemia. Biochem Biophys Res Commun 391(1):1039-42 |
abstractText | Nesfatin-1 is recently reported as a satiety molecule to suppress food intake via the melanocortin signaling in hypothalamus when injected centrally and peripherally. Here we report that nesfatin-1 is also anti-hyperglycemic. It was found that the intravenous injection of nesfatin-1 significantly reduced blood glucose in hyperglycemic db/db mice. This anti-hyperglycemic effect of nesfatin-1 was time-, dose-, insulin-dependent and peripheral. |