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Publication : Expression of Dpp6 in mouse embryonic craniofacial development.

First Author  Du J Year  2011
Journal  Acta Histochem Volume  113
Issue  6 Pages  636-9
PubMed ID  20817268 Mgi Jnum  J:166090
Mgi Id  MGI:4839695 Doi  10.1016/j.acthis.2010.08.001
Citation  Du J, et al. (2011) Expression of Dpp6 in mouse embryonic craniofacial development. Acta Histochem 113(6):636-9
abstractText  Dipeptidyl-peptidase-like protein 6 (DPP6), a member of the dipeptidyl aminopeptidase family, plays distinct roles in brain development, but its expression in embryonic craniofacial development is unknown. The expression pattern of Dpp6 in the maxillofacial region during mouse embryonic craniofacial development was analyzed by whole-mount in situ hybridization on sections and by real-time PCR analysis. Dpp6 expression was detected during mouse embryonic craniofacial development in embryos 11-13.5 days post-coitum (dpc). Real-time PCR showed high Dpp6 expression present in 11.5-13.5dpc, and this then decreased as development of maxillofacial region progressed. The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development.
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