First Author | Owada Y | Year | 2001 |
Journal | Histochem J | Volume | 33 |
Issue | 8 | Pages | 453-7 |
PubMed ID | 11931385 | Mgi Jnum | J:167686 |
Mgi Id | MGI:4878896 | Doi | 10.1023/a:1014420330284 |
Citation | Owada Y, et al. (2001) Localization of epidermal-type fatty acid binding protein in alveolar macrophages and some alveolar type II epithelial cells in mouse lung. Histochem J 33(8):453-7 |
abstractText | Almost all alveolar macrophages in the mouse lung were strongly immunoreactive for epidermal-type fatty acid binding protein. At the electron microscope level, the immunoreactive material was localized diffusely in the cytoplasm but not within the nucleus. A certain number of alveolar type II epithelial cells were also immunoreactive for the protein with variable immunointensity, while a substantial number of the type II cells were immunonegative. No immunoreactive interstitial fibroblasts were encountered. Based on the present findings, possible roles of epidermal-type fatty acid binding protein in the host-defence mechanism played by alveolar macrophages are suggested. |