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Publication : Localization of epidermal-type fatty acid binding protein in alveolar macrophages and some alveolar type II epithelial cells in mouse lung.

First Author  Owada Y Year  2001
Journal  Histochem J Volume  33
Issue  8 Pages  453-7
PubMed ID  11931385 Mgi Jnum  J:167686
Mgi Id  MGI:4878896 Doi  10.1023/a:1014420330284
Citation  Owada Y, et al. (2001) Localization of epidermal-type fatty acid binding protein in alveolar macrophages and some alveolar type II epithelial cells in mouse lung. Histochem J 33(8):453-7
abstractText  Almost all alveolar macrophages in the mouse lung were strongly immunoreactive for epidermal-type fatty acid binding protein. At the electron microscope level, the immunoreactive material was localized diffusely in the cytoplasm but not within the nucleus. A certain number of alveolar type II epithelial cells were also immunoreactive for the protein with variable immunointensity, while a substantial number of the type II cells were immunonegative. No immunoreactive interstitial fibroblasts were encountered. Based on the present findings, possible roles of epidermal-type fatty acid binding protein in the host-defence mechanism played by alveolar macrophages are suggested.
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