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Publication : Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

First Author  Chung YC Year  2011
Journal  Gene Expr Patterns Volume  11
Issue  1-2 Pages  84-92
PubMed ID  20932939 Mgi Jnum  J:168654
Mgi Id  MGI:4889170 Doi  10.1016/j.gep.2010.09.007
Citation  Chung YC, et al. (2011) Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns 11(1-2):84-92
abstractText  Transcription factor families are well known to be involved in the intrinsic pathways that regulate the organogenesis, early development, and microenvironment of the thymus. However, identification of the transcription factors (TFs) involved in the late development of the thymus, particularly later than embryonic day 15.5 (E15.5), is progressing slowly. In this study, we used in situ hybridization to screen numerous expression patterns of the TFs involved in the development of the mouse thymus. More than 400 members, including unique TFs and some transcription co-factors, were tested. Among the screened TFs, 160 were found to be expressed in the thymus after E15.5, and 74 of these were expressed in restricted areas.
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