First Author | Kasahara M | Year | 2011 |
Journal | Behav Brain Res | Volume | 218 |
Issue | 2 | Pages | 357-62 |
PubMed ID | 21192987 | Mgi Jnum | J:168751 |
Mgi Id | MGI:4938197 | Doi | 10.1016/j.bbr.2010.12.029 |
Citation | Kasahara M, et al. (2011) Influence of transgenic corticotropin-releasing factor (CRF) over-expression on social recognition memory in mice. Behav Brain Res 218(2):357-62 |
abstractText | We examined juvenile social recognition and discrimination in mice with early post-natal onset, transgenic CRF over-expression (CRF-OE) and in their wild-type littermates (WT). CRF-OE mice showed enhanced social investigation during the first encounter, normal short-term and facilitated long-term social recognition memory, compared to WT. These results suggest that chronically elevated brain CRF tone may contribute in better remembering ethologically relevant and emotionally salient stimuli, such as social interaction. |