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Publication : Genetic interactions in cancer progression and treatment.

First Author  Ashworth A Year  2011
Journal  Cell Volume  145
Issue  1 Pages  30-8
PubMed ID  21458666 Mgi Jnum  J:171192
Mgi Id  MGI:4948981 Doi  10.1016/j.cell.2011.03.020
Citation  Ashworth A, et al. (2011) Genetic interactions in cancer progression and treatment. Cell 145(1):30-8
abstractText  As cancer cell genomes are unveiled at a breathtaking pace, the genetic principles at play in cancer are emerging in all their complexity, prompting the assessment of classical genetic interaction models. Here, we discuss the implications of these findings for cancer progression and heterogeneity and for the development of new therapeutic approaches.
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