| First Author | Mansour MR | Year | 2011 |
| Journal | Cancer Cell | Volume | 20 |
| Issue | 5 | Pages | 559-61 |
| PubMed ID | 22094251 | Mgi Jnum | J:178956 |
| Mgi Id | MGI:5300669 | Doi | 10.1016/j.ccr.2011.10.027 |
| Citation | Mansour MR, et al. (2011) Discovery of a secreted tumor suppressor provides a promising therapeutic strategy for follicular lymphoma. Cancer Cell 20(5):559-61 |
| abstractText | In a recent paper in Cell, Oricchio et al. identify EPHA7 as a tumor suppressor gene residing in the 6q-deleted region in follicular lymphoma. A truncated EPHA7(TR) isoform is secreted by normal B cells, inhibits EPHA2 signaling, and, as a secreted tumor suppressor protein, has potential as a targeted therapeutic polypeptide. |
