| First Author | Barbacid M | Year | 2012 |
| Journal | Cancer Cell | Volume | 21 |
| Issue | 5 | Pages | 598-600 |
| PubMed ID | 22624710 | Mgi Jnum | J:189302 |
| Mgi Id | MGI:5445029 | Doi | 10.1016/j.ccr.2012.04.032 |
| Citation | Barbacid M (2012) Opening a new GATAway for treating KRAS-driven lung tumors. Cancer Cell 21(5):598-600 |
| abstractText | In a recent issue of Cell, Kumar and colleagues uncovered a synthetic lethal interaction between oncogenic KRAS and the transcription factor GATA2 in non-small cell lung carcinoma. Pharmacological inhibition of GATA2-mediated pathways with bortezomib and fasudil results in dramatic tumor inhibition. These observations unveil new armamentaria to fight this deadly disease. |
