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Publication : Controlling COR competence: BCL-6 regulates neurogenesis and tumor suppression.

First Author  Chiang C Year  2014
Journal  Cancer Cell Volume  26
Issue  6 Pages  773-774
PubMed ID  25490438 Mgi Jnum  J:217524
Mgi Id  MGI:5614500 Doi  10.1016/j.ccell.2014.11.020
Citation  Chiang C, et al. (2014) Controlling COR competence: BCL-6 regulates neurogenesis and tumor suppression. Cancer Cell 26(6):773-4
abstractText  In this issue of Cancer Cell, Tiberi and colleagues describe a tumor-suppressor role for BCL6. In the cerebellum, BCL6 is required for the transition from proliferative precursor cell to a more differentiated immature neuron through repressing the expression of Hedgehog effectors, thus controlling a pathway that is aberrantly activated in medulloblastoma.
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