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Publication : CD103+ dendritic cells producing interleukin-12 in anticancer immunosurveillance.

First Author  Zitvogel L Year  2014
Journal  Cancer Cell Volume  26
Issue  5 Pages  591-3
PubMed ID  25517740 Mgi Jnum  J:217736
Mgi Id  MGI:5615517 Doi  10.1016/j.ccell.2014.10.008
Citation  Zitvogel L, et al. (2014) CD103+ dendritic cells producing interleukin-12 in anticancer immunosurveillance. Cancer Cell 26(5):591-3
abstractText  The mechanisms through which tumor antigen-specific T cells are elicited in natural or chemotherapy-induced immunosurveillance have been elusive. In this issue of Cancer Cell, two papers by Broz and colleagues and Ruffell and colleagues delineate an important role for a specific dendritic cell subset characterized by CD103 expression, dependence on transcription factors Batf3 and Irf8, and interleukin-12 production.
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