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Publication : SPSB1 may have MET its match during breast cancer recurrence.

First Author  Qin Y Year  2014
Journal  Cancer Discov Volume  4
Issue  7 Pages  760-1
PubMed ID  25002612 Mgi Jnum  J:217925
Mgi Id  MGI:5616059 Doi  10.1158/2159-8290.CD-14-0505
Citation  Qin Y, et al. (2014) SPSB1 may have MET its match during breast cancer recurrence. Cancer Discov 4(7):760-1
abstractText  SUMMARY: Disease recurrence is the most common cause of death for patients with breast cancer, yet little is known about the molecular mechanisms underlying this process. Using inducible transgenic mouse model systems, Feng and colleagues identified SPSB1 as a determinant of breast cancer recurrence by virtue of its ability to protect tumor cells from apoptosis through c-MET activation.
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