| First Author | Izumchenko E | Year | 2015 |
| Journal | Cancer Discov | Volume | 5 |
| Issue | 5 | Pages | 472-4 |
| PubMed ID | 25941338 | Mgi Jnum | J:225617 |
| Mgi Id | MGI:5693710 | Doi | 10.1158/2159-8290.CD-15-0336 |
| Citation | Izumchenko E, et al. (2015) Understanding the MIG6-EGFR Signaling Axis in Lung Tumorigenesis. Cancer Discov 5(5):472-4 |
| abstractText | With multiple clinical trials under way targeting mutant EGFR in patients with lung cancer, Maity and colleagues address important aspects of a MIG6-EGFR signaling axis using genetically engineered mouse models expressing mutated EGFRs on the MIG6-deficient background. This study extends our understanding of EGFR regulation by MIG6 and reveals that MIG6 antagonizes tumor formation in mutant EGFR-driven lung adenocarcinoma. |
