| First Author | Vo TT | Year | 2015 |
| Journal | Cancer Discov | Volume | 5 |
| Issue | 7 | Pages | 697-700 |
| PubMed ID | 26152921 | Mgi Jnum | J:227234 |
| Mgi Id | MGI:5699947 | Doi | 10.1158/2159-8290.CD-15-0609 |
| Citation | Vo TT, et al. (2015) INPP4B Is a Tumor Suppressor in the Context of PTEN Deficiency. Cancer Discov 5(7):697-700 |
| abstractText | Enzymes (PI3K and PTEN) controlling cellular levels of 3-phosphorylated phosphoinositides are known as important drivers or suppressors of tumorigenesis in various cancers. In this issue of Cancer Discovery, Kofuji and colleagues and Chew and colleagues identify the lipid phosphatase INPP4B as a context-specific tumor suppressor that controls phosphoinositide levels and AKT2 activation in PTEN-deficient cells. |
