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Publication : Tobacco Causes Human Cancers--A Concept Founded on Epidemiology and an Insightful Experiment Now Requires Translation Worldwide.

First Author  Loeb LA Year  2016
Journal  Cancer Res Volume  76
Issue  4 Pages  765-6
PubMed ID  26880808 Mgi Jnum  J:231449
Mgi Id  MGI:5771590 Doi  10.1158/0008-5472.CAN-16-0149
Citation  Loeb LA (2016) Tobacco Causes Human Cancers-A Concept Founded on Epidemiology and an Insightful Experiment Now Requires Translation Worldwide. Cancer Res 76(4):765-6
abstractText  The recognition that tobacco smoke is carcinogenic led to the most significant and successful effort at reducing cancer incidence in human history. A major milestone of this effort was the publication in Cancer Research by Wynder and colleagues, which demonstrated the ability of tobacco tars to produce tumors in mice. This study provided a powerful link between the epidemiology of cancer and mechanisms of carcinogenesis. This commentary asserts that we have a moral obligation to translate our success in reducing lung cancer in the United States to the 1.25 billion smokers throughout the rest of the world. Cancer Res; 76(4); 765-6. (c)2016 AACR.See related article by Wynder et al., Cancer Res 1953;13:855-64.
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