First Author | Loeb LA | Year | 2016 |
Journal | Cancer Res | Volume | 76 |
Issue | 4 | Pages | 765-6 |
PubMed ID | 26880808 | Mgi Jnum | J:231449 |
Mgi Id | MGI:5771590 | Doi | 10.1158/0008-5472.CAN-16-0149 |
Citation | Loeb LA (2016) Tobacco Causes Human Cancers-A Concept Founded on Epidemiology and an Insightful Experiment Now Requires Translation Worldwide. Cancer Res 76(4):765-6 |
abstractText | The recognition that tobacco smoke is carcinogenic led to the most significant and successful effort at reducing cancer incidence in human history. A major milestone of this effort was the publication in Cancer Research by Wynder and colleagues, which demonstrated the ability of tobacco tars to produce tumors in mice. This study provided a powerful link between the epidemiology of cancer and mechanisms of carcinogenesis. This commentary asserts that we have a moral obligation to translate our success in reducing lung cancer in the United States to the 1.25 billion smokers throughout the rest of the world. Cancer Res; 76(4); 765-6. (c)2016 AACR.See related article by Wynder et al., Cancer Res 1953;13:855-64. |