First Author | Leelatian N | Year | 2016 |
Journal | Cancer Cell | Volume | 29 |
Issue | 5 | Pages | 613-615 |
PubMed ID | 27165737 | Mgi Jnum | J:231896 |
Mgi Id | MGI:5775478 | Doi | 10.1016/j.ccell.2016.04.007 |
Citation | Leelatian N, et al. (2016) Head of the Class: OLIG2 and Glioblastoma Phenotype. Cancer Cell 29(5):613-5 |
abstractText | Genomic mapping has driven the classification of glioblastoma into distinct molecular subclasses, but mechanisms that regulate tumor subclass phenotypes are only now emerging. In this issue of Cancer Cell, Lu et al. describe a phenotypic switch from PDGFRA-enriched "proneural" to EGFR-enriched "classical" features in glioblastoma upon ablation of Olig2. |