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Publication : Pancreatic Cancer: Planning Ahead for Metastatic Spread.

First Author  Stromnes IM Year  2016
Journal  Cancer Cell Volume  29
Issue  6 Pages  774-776
PubMed ID  27300430 Mgi Jnum  J:232331
Mgi Id  MGI:5776627 Doi  10.1016/j.ccell.2016.05.013
Citation  Stromnes IM, et al. (2016) Pancreatic Cancer: Planning Ahead for Metastatic Spread. Cancer Cell 29(6):774-6
abstractText  Metastasis and therapy resistance are cardinal features of pancreatic ductal adenocarcinoma, a commonly lethal malignancy. In this issue of Cancer Cell, Steele et al. show that CXCR2 expression and neutrophils are required for metastasis. In mice treated with advanced disease, inhibiting both CXCR2 and PD1 cooperatively but not individually prolongs survival.
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