First Author | Stromnes IM | Year | 2016 |
Journal | Cancer Cell | Volume | 29 |
Issue | 6 | Pages | 774-776 |
PubMed ID | 27300430 | Mgi Jnum | J:232331 |
Mgi Id | MGI:5776627 | Doi | 10.1016/j.ccell.2016.05.013 |
Citation | Stromnes IM, et al. (2016) Pancreatic Cancer: Planning Ahead for Metastatic Spread. Cancer Cell 29(6):774-6 |
abstractText | Metastasis and therapy resistance are cardinal features of pancreatic ductal adenocarcinoma, a commonly lethal malignancy. In this issue of Cancer Cell, Steele et al. show that CXCR2 expression and neutrophils are required for metastasis. In mice treated with advanced disease, inhibiting both CXCR2 and PD1 cooperatively but not individually prolongs survival. |