First Author | Watanabe T | Year | 2016 |
Journal | Cancer Cell | Volume | 30 |
Issue | 1 | Pages | 3-5 |
PubMed ID | 27411579 | Mgi Jnum | J:233527 |
Mgi Id | MGI:5784934 | Doi | 10.1016/j.ccell.2016.06.011 |
Citation | Watanabe T, et al. (2016) Context, Context, Context: New Gene Programs Linked to Bad Behavior in MLL-AF9-Initiated Leukemia. Cancer Cell 30(1):3-5 |
abstractText | In this issue of Cancer Cell, Stavropoulou et al. report that expression of the MLL-AF9 fusion results in acute myelogenous leukemia (AML) with different behaviors depending on cell context, which leads them to identify a transcriptional signature surprisingly resembling that of the epithelial-to-mesenchymal (EMT) transition, correlating with aggressiveness of disease. |