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Publication : IDH1, Histone Methylation, and So Forth.

First Author  Penard-Lacronique V Year  2016
Journal  Cancer Cell Volume  30
Issue  2 Pages  192-194
PubMed ID  27505668 Mgi Jnum  J:234908
Mgi Id  MGI:5792429 Doi  10.1016/j.ccell.2016.07.008
Citation  Penard-Lacronique V, et al. (2016) IDH1, Histone Methylation, and So Forth. Cancer Cell 30(2):192-4
abstractText  IDH mutants cause aberrant DNA and histone methylation and contribute to hematological and neuronal malignancies. In this issue of Cancer Cell, Inoue et al. describe a potential specific effect of IDH1 mutations that reduces Atm expression via inhibition of H3K9 demethylases, which may represent a first step toward cellular transformation.
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