| First Author | Jabri B | Year | 2017 |
| Journal | J Immunol | Volume | 198 |
| Issue | 8 | Pages | 3005-3014 |
| PubMed ID | 28373482 | Mgi Jnum | J:252365 |
| Mgi Id | MGI:5927068 | Doi | 10.4049/jimmunol.1601693 |
| Citation | Jabri B, et al. (2017) T Cells in Celiac Disease. J Immunol 198(8):3005-3014 |
| abstractText | Celiac disease is a human T cell-mediated autoimmune-like disorder caused by exposure to dietary gluten in genetically predisposed individuals. This review will discuss how CD4 T cell responses directed against an exogenous Ag can cause an autoreactive B cell response and participate in the licensing of intraepithelial lymphocytes to kill intestinal epithelial cells. Furthermore, this review will examine the mechanisms by which intraepithelial cytotoxic T cells mediate tissue destruction in celiac disease. |
