| First Author | Shibuya A | Year | 2017 |
| Journal | Int Immunol | Volume | 29 |
| Issue | 11 | Pages | 519-524 |
| PubMed ID | 29281010 | Mgi Jnum | J:256417 |
| Mgi Id | MGI:6108083 | Doi | 10.1093/intimm/dxx059 |
| Citation | Shibuya A, et al. (2017) A pro-inflammatory role of Fcalpha/muR on marginal zone B cells in sepsis. Int Immunol 29(11):519-524 |
| abstractText | Fc receptors play important roles for a wide array of immune responses. In contrast to the well-defined Fcgamma and Fcepsilon receptors, the molecular and functional characteristics of Fc receptors for IgA and IgM have remained incompletely understood for years. Recent progress has unveiled the characteristics of Fc receptors for IgA and IgM, including Fcalpha/mu receptor (Fcalpha/muR) (CD351), polymeric immunoglobulin receptor (poly-IgR), Fcalpha receptor (FcalphaRI) (CD89) and Fcmu receptor (FcmuR). In this review, we summarize the molecular and functional characteristics of Fcalpha/muR in comparison with poly-IgR, FcmuR and FcalphaRI, and focus particularly on the pro-inflammatory function of Fcalpha/muR expressed on marginal zone B cells in sepsis. |
