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Publication : MicroRNA-133 mediates cardiac diseases: Mechanisms and clinical implications.

First Author  Liu Y Year  2017
Journal  Exp Cell Res Volume  354
Issue  2 Pages  65-70
PubMed ID  28322824 Mgi Jnum  J:260900
Mgi Id  MGI:6152035 Doi  10.1016/j.yexcr.2017.03.037
Citation  Liu Y, et al. (2017) MicroRNA-133 mediates cardiac diseases: Mechanisms and clinical implications. Exp Cell Res 354(2):65-70
abstractText  MicroRNAs (miRNAs) belong to the family of small non-coding RNAs that mediate gene expression by post-transcriptional regulation. Increasing evidence have demonstrated that miR-133 is enriched in muscle tissues and myogenic cells, and its aberrant expression could induce the occurrence and development of cardiac disorders, such as cardiac hypertrophy, heart failure, etc. In this review, we summarized the regulatory roles of miR-133 in cardiac disorders and the underlying mechanisms, which suggest that miR-133 may be a potential diagnostic and therapeutic tool for cardiac disorders.
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