| First Author | Li JWY | Year | 2018 |
| Journal | Mol Cell Endocrinol | Volume | 469 |
| Pages | 98-106 | PubMed ID | 28965973 |
| Mgi Jnum | J:263920 | Mgi Id | MGI:6163931 |
| Doi | 10.1016/j.mce.2017.09.032 | Citation | Li JWY, et al. (2018) MENIN loss as a tissue-specific driver of tumorigenesis. Mol Cell Endocrinol 469:98-106 |
| abstractText | The MEN1 gene encodes MENIN, a tumor suppressor that plays a role in multiple cellular processes. Germline and somatic mutations in MEN1 have been identified in hereditary and sporadic tumors of neuroendocrine origins suggesting context-specific functions. In this review, we focus on the development of mutational Men1 in vivo models, the known cellular activities of MENIN and efforts to identify vulnerabilities in tumors with MENIN loss. |
