First Author | Accili D | Year | 1997 |
Journal | Trends Endocrinol Metab | Volume | 8 |
Issue | 3 | Pages | 101-4 |
PubMed ID | 18406794 | Mgi Jnum | J:41329 |
Mgi Id | MGI:893754 | Doi | 10.1016/s1043-2760(97)00031-3 |
Citation | Accili D (1997) Insulin receptor knock-out mice. Trends Endocrinol Metab 8(3):101-4 |
abstractText | Targeted mutagenesis of the insulin receptor gene in mice has yielded unexpected results. This article reviews recent findings and analyzes this animal model can further our understanding of the mechanism of insulin action and its impairment in non-insulin-dependent diabetes mellitus is analyzed. (Trends Endocrinol Metab 1997;8:101-104). Published 1997 by Elsevier Science Inc. |