| First Author | Kimura S | Year | 1980 |
| Journal | Immunogenetics | Volume | 10 |
| Issue | 4 | Pages | 363-72 |
| PubMed ID | 22457928 | Mgi Jnum | J:4451 |
| Mgi Id | MGI:52940 | Doi | 10.1007/bf01561586 |
| Citation | Kimura S, et al. (1980) A new lymphocyte alloantigen (Ly-10) controlled by a gene linked to the Lyt-1 locus. Immunogenetics 10(4):363-72 |
| abstractText | Spleen cells from a (BALB/c x C57BL/6)F1 mouse immunized with CBA/J spleen cells were fused with the myeloma cell line NS-1. One of the six established hybrid cell lines continuously secreted antibody that recognized a new antigenic specificity, tentatively called "Ly-10.1". This newly found antigen is expressed on thymocytes, on splenic T and B cells, on bone-marrow cells, and on the cells derived from brain, kidney and liver. It is also expressed on a continuous cell line, 416B, with stem-cell characteristics. The unique tissue distribution and, furthermore, a distinct strain distribution pattern distinguishes Ly-10.1 from any known murine lymphocyte alloantigen. On the basis of reactivity with cells of the C57BL/6-Lyt-1a congenic strain, one gene governing Ly-10 expression is assigned to the Lyt-1 region of chromosome 19. |
