| First Author | Graff RJ | Year | 1978 |
| Journal | Immunogenetics | Volume | 7 |
| Issue | 1 | Pages | 413-23 |
| PubMed ID | 21302096 | Mgi Jnum | J:4438 |
| Mgi Id | MGI:52930 | Doi | 10.1007/BF01844032 |
| Citation | Graff RJ, et al. (1978) The alleles of the H-13 locus. Immunogenetics 7(1):413-23 |
| abstractText | Seven congenic strains differing from C57BL/10Sn at theH-13 locus have been produced which define fourH-13 alleles. Isografting, exchanging of grafts between sublines, F(1) testing, and linkage testing demonstrate the presence of additionalH genes in four of these strains. The medial survival times (MSTs) of skin grafts fromH-13(a) to unimmunizedH-13(b) recipients ranged from 69 to 83 days. Rejection across all other barriers was extremely weak with most MSTs being > 100 days. Preinjection of donor strain thymocytes caused accelerated rejection of skin grafts fromH-13(a) toH-13(b) mice, but had only minimal effect on skin grafts across other barriers. Rejection ofH-13 incompatible grafts was significantly stronger when the donor and host areH-3(a) than when they wereH-3(b). |
