| First Author | Satou K | Year | 2015 |
| Journal | J Vet Med Sci | Volume | 77 |
| Issue | 6 | Pages | 753-9 |
| PubMed ID | 25716571 | Mgi Jnum | J:285523 |
| Mgi Id | MGI:6400197 | Doi | 10.1292/jvms.14-0423 |
| Citation | Satou K, et al. (2015) Effect of the Y chromosome on testis weight in mice. J Vet Med Sci 77(6):753-9 |
| abstractText | We investigated the effect of the Y chromosome on testis weight in (B6.Cg-A(y) x Y-consomic mouse strain) F1 male mice. We obtained the following results: (1) Mice with the Mus musculus domesticus-type Y chromosome had significantly heavier testis than those with the M. m. musculus-type Y chromosome. (2) Variations in Usp9y and the number of CAG repeats in Sry were significantly associated with testes weight. The A(y) allele was correlated with a reduced testis weight, and the extent of this reduction was significantly associated with a CAG repeat number polymorphism in Sry. These results suggest that Y chromosome genes not only influence testis weight but also modify the effect of the A(y) allele in mediating this phenomenon. |
