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Publication : A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

First Author  Casanova JL Year  2020
Journal  Cell Volume  181
Issue  6 Pages  1194-1199
PubMed ID  32405102 Mgi Jnum  J:291463
Mgi Id  MGI:6442233 Doi  10.1016/j.cell.2020.05.016
Citation  Casanova JL, et al. (2020) A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection. Cell 181(6):1194-1199
abstractText  SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers-individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease-present a unique opportunity to reveal human genetic determinants of infection and disease.
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