|  Help  |  About  |  Contact Us

Publication : NOTCH Your Usual Suspect: MYC Charged with Controlling Neuroendocrine Cell-Fate in Small Cell Lung Cancer.

First Author  Ng J Year  2020
Journal  Cancer Cell Volume  38
Issue  1 Pages  17-20
PubMed ID  32663464 Mgi Jnum  J:293705
Mgi Id  MGI:6448335 Doi  10.1016/j.ccell.2020.06.009
Citation  Ng J, et al. (2020) NOTCH Your Usual Suspect: MYC Charged with Controlling Neuroendocrine Cell-Fate in Small Cell Lung Cancer. Cancer Cell 38(1):17-20
abstractText  Small cell lung cancer (SCLC) is highly heterogeneous. In this issue of Cancer Cell, Ireland et al. demonstrate that MYC mediates neuroendocrine cell plasticity in SCLC by activating NOTCH signaling. This MYC-NOTCH axis controls the dynamic behavior of tumor cells, resulting in the co-existence of SCLC subtypes within individual tumors.
Quick Links:
 
Quick Links:
 

Expression

Publication --> Expression annotations

 

Other

2 Authors

0 Bio Entities

0 Expression