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Publication : <i>In vivo</i> regeneration of neo-nephrons in rodents by renal progenitor cell transplantation.

First Author  Yamanaka S Year  2021
Journal  STAR Protoc Volume  2
Issue  1 Pages  100314
PubMed ID  33554147 Mgi Jnum  J:303420
Mgi Id  MGI:6512174 Doi  10.1016/j.xpro.2021.100314
Citation  Yamanaka S, et al. (2021) In vivo regeneration of neo-nephrons in rodents by renal progenitor cell transplantation. STAR Protoc 2(1):100314
abstractText  Renal progenitor cells induced from pluripotent stem cells have attracted attention as a cell source for organ regeneration. Here, we report an in vivo protocol for the regeneration of urine-producing nephrons, i.e., neo-nephrons, in mice. We outline steps to transplant exogenous renal progenitor cells into the nephrogenic zone of transgenic mice and subsequently analyze these neo-nephrons. For complete details on the use and execution of this protocol, please refer to Fujimoto et al. (2020).
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