First Author | Lee CH | Year | 2005 |
Journal | Biochem Genet | Volume | 43 |
Issue | 11-12 | Pages | 597-602 |
PubMed ID | 16382364 | Mgi Jnum | J:309260 |
Mgi Id | MGI:6708816 | Doi | 10.1007/s10528-005-9116-5 |
Citation | Lee CH, et al. (2005) A new variant of the mouse Akp1 locus. Biochem Genet 43(11-12):597-602 |
abstractText | A new electrophoretic migration type of alkaline phosphatase 1 (Akp1) was found on the cellulose acetate electrophoresis for kidney and liver homogenates of KWHM mouse, a newly established inbred strain derived from the Korean wild mouse (Mus musculus molossinus). This new type of alkaline phosphatase 1 was distinguished from previously reported AKP1A and AKP1B types in the mouse, and tentatively named AKP1C. In genetic analysis by mating experiments between KWHM and C57BL/6J (AKP1A) or BALB/cA (AKP1B), the phenotypic segregation ratios of AKP1A : AKP1AC : AKP1C or AKP1B : AKP1BC : AKP1C were 1 : 2 : 1 in both groups of F2 generations. It was therefore concluded that AKP1C type is controlled by Akp1c allele which is codominant with Akp1a and Akp1b alleles. |