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Publication : Association between intermale aggression and genetically- defined tryptophan hydroxylase activity in the mouse brain.

First Author  Kulikov A Year  1996
Journal  Aggress Behav Volume  22
Issue  2 Pages  111-117
Mgi Jnum  J:33967 Mgi Id  MGI:81447
Doi  10.1002/(SICI)1098-2337(1996)22:2<111::AID-AB4>3.0.CO;2-R Citation  Kulikov A, et al. (1996) Association between intermale aggression and genetically- defined tryptophan hydroxylase activity in the mouse brain. Aggress Behav 22(2):111-117
abstractText  The relationship between the genetically defined intensity of intermale aggression and the activity of brain tryptophan hydroxylase (TPH) has been studied in inbred mice. No association between the enzyme activity and the percentage of aggressive mice (reflecting the predisposition to aggressive reaction) was revealed. However, a significant positive interstrain correlation between brain TPH activity and accumulated attacking time (reflecting fight intensity) was identified. No correlation was found between TPH activity and the accumulated attacking time in segregating F2 (BALE x C57BL) mice. In conclusion, TPH is an important, but not the only factor controlling the intensity of intermale aggression in mice. (C) 1996 Wiley-Liss, Inc.
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