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Publication : Transcriptomic profiling comparison of YAP over-expression and conditional knockout mouse tooth germs.

First Author  Liu M Year  2015
Journal  Genom Data Volume  5
Pages  228-30 PubMed ID  26484260
Mgi Jnum  J:355987 Mgi Id  MGI:7762079
Doi  10.1016/j.gdata.2015.05.038 Citation  Liu M, et al. (2015) Transcriptomic profiling comparison of YAP over-expression and conditional knockout mouse tooth germs. Genom Data 5:228-30
abstractText  To identify the downstream target genes of YAP, we used RNA-Seq technology to compare the transcriptomic profilings of Yap conditional knockout (Yap CKO) and YAP over-expression mouse tooth germs. Our results showed that some Hox, Wnt and Laminin family genes had concurrent changes with YAP transcripts, indicating that the expression of these genes may be regulated by YAP. Here, we provide the detailed experimental procedure for the transcriptomic profiling results (NCBI GEO accession number GSE65524). The associated study on the regulation of Hoxa1 and Hoxc13 genes by YAP was published in Molecular Cellular Biology in 2015 [Liu et al., 2015].
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