| Primary Identifier | IPR047465 | Type | Family |
| Short Name | Dpy19L3 |
| description | This entry represents a probable C-mannosyltransferase by its similarity to Dpy-19. It is known as Dpy-19-like protein 3 (DPY19L3).Dpy19 proteins are C-mannosyltransferases that mediate C-mannosylation of tryptophan residues on target proteins. C-mannosylation is the attachment of alpha-mannose to the indole C2 carbon of the first tryptophan residue in the consensus amino acid sequence Trp-Xaa-Xaa-Trp/Cys through a C-C bond. This reaction takes place in the endoplasmic reticulum (ER) lumen. Dpy19 is a transmembrane domain family whose name is derived from the Caenorhabditis elegans Dumpy mutant [, ]. |
