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Protein Domain : Vacuolar membrane protease, C-terminal domain

Primary Identifier  IPR053975 Type  Domain
Short Name  PFF1_C
description  This entry includes fungal vacuolar membrane proteases, such as PFF1 from yeast, which may be involved in vacuolar sorting and osmoregulation []. It is an homologue of human ERMP1 [].According to AlphaFold structure predictions, these proteins consist of a M28 peptidase domain () at the N-terminal, a central transmembrane domain () and a C-terminal domain with an elongated ��-sandwich-like fold, similar to the Mu homology domain (MHD) (). This entry represents the C-terminal MHD-like domain of PFF1 and its fungal homologues.

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0 Protein Domain Regions