| Primary Identifier | IPR053976 | Type | Domain |
| Short Name | PFF1_TM |
| description | This entry includes fungal vacuolar membrane proteases, such as PFF1 from yeast, which may be involved in vacuolar sorting and osmoregulation []. It is the homologue of human ERMP1 [].According to AlphaFold structure predictions, these proteins consist of a M28 peptidase domain () at the N-terminal, a central transmembrane domain (TM) and a C-terminal domain with an elongated ��-sandwich-like fold (), similar to the Mu homology domain (MHD) (). This entry represents the TM domain of PFF1 and its fungal homologues. |
