| Primary Identifier | IPR063324 | Type | Domain |
| Short Name | NELL_VWC_C |
| description | This entry represents a C-terminal domain of approximately 60 residues found in NELL1 and NELL2 (NEL-like proteins) in vertebrates. This domain is located after the VWC domains () and multiple EGF-like domains (). NELL proteins are secreted glycoproteins that form homotrimers and function as PKC-binding proteins. NELL1 promotes osteoblast differentiation while NELL2 functions in axon guidance through binding to ROBO3 receptor. |
