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Protein Domain : Endoplasmic reticulum metallopeptidase 1-like, M28 peptidase domain

Primary Identifier  IPR048024 Type  Domain
Short Name  Fxna-like_M28_dom
description  Endoplasmic reticulum metallopeptidase 1 (ERMP1, also known as Felix-ina, FXNA or Fxna peptidase) is a multi-pass membrane protein located in the endoplasmic reticulum membrane. In humans, Fxna may play a crucial role in processing proteins required for the organisation of somatic cells and oocytes into discrete follicular structures, although which proteins are hydrolysed has not yet been determined []. This entry also includes vacuolar membrane proteases from fungi, such as PFF1 from yeast which are homologues of human ERMP1 []. PFF1 may be involved in vacuolar sorting and osmoregulation [].

0 Child Features

1 Parent Features

2 Protein Domain Regions