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Protein Domain : Little elongation complex subunit 1, C-terminal, insects

Primary Identifier  IPR063802 Type  Domain
Short Name  Ice1_insects_C
description  This entry represents the C-terminal domain of little elongation complex subunit 1 (Ice1) found in insects. The full-length Ice1 protein is a component of the little elongation complex (LEC), which is required to regulate small nuclear RNA gene transcription by RNA polymerase II and III [, ]. Ice1 acts as a scaffold protein that promotes LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies. The complete protein is located in the nucleus and belongs to the ICE1 family. The specific function of this domain remains to be determined. This domain contains a TPR-like fold.

0 Child Features

0 Parent Features

0 Protein Domain Regions