| Primary Identifier | IPR048832 | Type | Domain |
| Short Name | PCF11_charged |
| description | This entry represents the charged region found in the Pre-mRNA cleavage complex 2 protein (Pcf11) from human and the orthologues from vertebrates []. PCF11 is a subunit and an essential component of the pre-mRNA cleavage complex II (CFII), the orthologue of yeast cleavage and polyadenylation factor IA (CFIA), which is involved in pre-mRNA 3' end processing and in transcription termination[]. PCF11-mediated termination is essential for vertebrate development []. |