| Primary Identifier | IPR058537 | Type | Repeat |
| Short Name | TPR_TNPO3_IPO13_4th |
| description | This entry represents the third TPR domain found in Transportin-3 (TNPO3) from animals, as well as orthologues MTR10and uncharacterised protein YNR7 from yeast and MOS14 from plants. This entry also includes Importin-13 (IPO3) from animals. This domain interacts with the RS region of the ASF protein for nuclear transport [].These proteins are involved in transport of target proteins into the nucleus. TNPO3 mediates the nuclear import of splicing factor serine/arginine (SR) proteins, such as RBM4, SFRS1 and SFRS2, by recognising phosphorylated SR domains [, ]. |
