| Primary Identifier | IPR054504 | Type | Domain |
| Short Name | PWWP_KDM3B |
| description | This domain is found in Lysine-specific demethylase 3B (KDM3B, also known as JmjC domain-containing histone demethylation protein 2B or JHDM2B), Lysine-specific demethylase 3A (KDM3A, also known as JmjC domain-containing histone demethylation protein 2A or JHDM2A) and related proteins. KDM3B is a histone demethylase that specifically demethylates lysine at position 9 of histone H3 []. This enzyme plays a central role in histone code. This domain is predicted to adopt an open ��-barrel with an SH3-like topology. It has detectable sequence and structural similarity to PWWP reader domains of LEDGF and ZMYND8 known to recognise the histone H3 methylation marks of lysine at position 36. |
