| Primary Identifier | IPR061999 | Type | Domain |
| Short Name | CDH23_a-b |
| description | This entry represents an ��/�� domain found in the vertebrate Cadherin-23 (CDH23) and related proteins, including their orthologues in fruit fly Cadherin-87A and Cadherin-89D. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organisation of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development [, ]. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells []. |
