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Protein Domain : Poxvirus F5/Telomere-binding protein I6 domain

Primary Identifier  IPR007674 Type  Domain
Short Name  Poxvirus_F5/I6_dom
description  This entry represents a domain found in 36 kDa major membrane protein F5 and Telomere-binding protein I6 from Vaccinia virus, and similar sequences from poxvirus. F5, also named Protein OPG049, plays a role in the spread of virus to neighbouring cells ex vivo []. I6, also known as Telomere-binding protein OPG082, binds tightly and with great specificity to the hairpin form of the viral telomeric sequence. This telomere binding protein is thought to play a role in the initiation of vaccinia virus genome replication and/or genome encapsidation [, ].

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