| Primary Identifier | IPR052852 | Type | Family |
| Short Name | SSU_Processome_Comp |
| description | This family of proteins is involved in the early stages of ribosome biogenesis, specifically in the assembly of the small subunit (SSU) processome. These proteins are found in the nucleolus and are associated with the nascent pre-ribosomal RNA. They collaborate with ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins to facilitate RNA folding, chemical modifications, structural rearrangements, and cleavage. Additionally, they contribute to the targeted degradation of pre-ribosomal RNA by the RNA exosome. A key regulatory function of these proteins is to prevent the premature recruitment of the helicase DHX37 during the pre-ribosomal RNA processing stages. |
