| Primary Identifier | IPR052968 | Type | Family |
| Short Name | Nucleotide_metab_enz |
| description | This family of prokaryotic proteins includes enzymes involved in nucleotide metabolism. Some members of this family are capable of degrading RNA oligonucleotides, particularly those with a length of five nucleotides, by cleaving them from the 3' to 5' direction. They exhibit a preference for adenine-rich RNA sequences and show reduced activity on shorter oligonucleotides or those with a length of 24 nucleotides []. Additionally, some family members possess the ability to hydrolyse cyclic nucleotides such as cAMP and cGMP into their corresponding 5'-monophosphates, without exhibiting phosphohydrolase activity towards phospholipids or phosphorylated sugars []. The enzymatic activities of these proteins are crucial for the regulation of intracellular nucleotide levels and the maintenance of RNA turnover. |