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Protein Domain : Coiled-coil domain-containing protein 15

Primary Identifier  IPR037693 Type  Family
Short Name  CCDC15
description  CCDC15 protein plays an important role in primary cilium assembly, maintenance, and length regulation []. CCDC15 localises to the inner scaffold structure in the central region of centrioles and interacts with centriole inner scaffold proteins including POC5, POC1B, CETN2 and FAM161A to promote proper centriole size and integrity []. The protein is required for recruitment of the inner scaffold protein POC1B and the distal SFI1/CETN2 complex to centrioles []. CCDC15 contains multiple coiled-coil regions throughout its length []. This protein has established functions in centriole assembly and cilium biogenesis [].

0 Child Features

0 Parent Features

2 Protein Domain Regions