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Protein Domain : Arylsulfatase B

Primary Identifier  IPR047115 Type  Family
Short Name  ARSB
description  This family represents Arylsulfatase B (ARSB) and its paralogues, ARSI and ARSJ. ARSB removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation [, ]. It is involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium []. ARSI displays arylsulfatase activity at neutral pH, when co-expressed with SUMF1. Arylsulfatase activity has been detected in the secretion medium of retinal cell line, but no activity has been recorded when measured in cell extracts [, ].

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0 Parent Features

8 Protein Domain Regions