| Primary Identifier | IPR057050 | Type | Domain |
| Short Name | RRM_PARP14_2 |
| description | This domain is found in human Protein mono-ADP- ribosyltransferase PARP14 and related proteins. It is an RRM domain found second in PARP14.PARP14 is a large multidomain protein which in the N-terminal half contains a series of consecutive RRM and KH domains that are known to be nucleic acid-binding. PARP14 is involved in multiple signaling pathways linked to cancer, inflammation, and infection. PARP14 is an ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate residues on target proteins [, , ]. In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation []. |
