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CL Term : pre-B-I cell [CL:0000956] Cell Ontology
Obsolete  false
description  A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.
  • synonyms:
  • pre-BI cell,
  • pro-B cell (Philadelphia nomenclature)
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