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CL Term : intestinal fibroblastic reticular cell [CL:4052004] Cell Ontology

Obsolete  false
description  A specialized fibroblastic reticular cell that is part of gut-associated lymphoid tissue (GALT), responsible for forming a structural network that facilitates immune cell interactions. This cell is found in Peyer's patches, cryptopatches, and isolated lymphoid follicles. It plays crucial roles in maintaining intestinal immunity by controlling innate lymphoid cell homeostasis and function, organizing lymphoid structures, and contributing to intestinal microbiome balance.
  • synonyms:
  • Ccl19-expressing fibroblastic reticular cell,
  • solitary intestinal lymphoid tissue fibroblastic reticular cell,
  • gut-associated secondary lymphoid organs fibroblastic reticular cell
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